Brad Anderson created the decades-running newspaper comic strip, about a mischievous Great Dane who lives with the Winslow family, in 1954. The big dog then appeared in several animated episodes of "Heathcliff" and "Garfield and Friends."
Director: Tom Dey
Writer: Vince Di Meglio
Studio: 20th Century Fox
Cast: Owen Wilson, Emma Stone, Christopher Mintz-Plasse
Release: June 4, 2010